Researchers discover the mechanism by which tumor cells become resistant to chemotherapy in colorectal cancer
A large number of cancer patients are treated with platinum-based therapy. However, many tumors are capable of developing resistance to treatment. In this study, the researchers examined tumor samples from patients and pre-clinical models of colorectal cancer to better understand the resistance to platinum-based therapy.
A Unique Case of Gallbladder Agenesis and Cholangiocarcinoma
Gallbladder agenesis is a rare congenital anomaly of the biliary tract, due to failure of the gallbladder and cystic duct budding off of the common bile duct during fetal development.
Hernia—a common, treatable condition no one talks about
While an impending storm will trigger cautionary news reports about the risk of a heart attack while shoveling snow, you're less likely to hear how twisting and turning while moving heavy amounts of the tiny ice crystals may increase your risk of developing a hernia.
A promising discovery in the fight against incurable cancers
Galectin-9, a protein found in all mammals, is responsible for regulating human immune responses. It is of particular interest due to its ability to suppress the anticancer activities of T-cells—a type of white blood cell that is part of the immune system and can be used to help fight cancer.
No significant differences in postoperative complications found between open repair with local anesthesia and laparoscopic repair of inguinal hernias
In this retrospective cohort study, among 107 073 patients, no significant difference was found in complications between patients undergoing laparoscopic surgery and open repair with local anesthesia.
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